Metal-free oxidative ipso-carboacylation of alkynes: synthesis of 3-acylspiro [4, 5] trienones from n-arylpropiolamides and aldehydes

XH Ouyang, RJ Song, Y Li, B Liu…

Index: Poingdestre, Sarah-Jane; Goodacre, Jonathan D.; Weller, Andrew S.; Willis, Michael C. Chemical Communications, 2012 , vol. 48, # 51 p. 6354 - 6356

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Citation Number: 29

Abstract

... one of the most popularly fundamental processes in organic synthesis and chemical industries ... B, followed by selective ipso-carbocyclization to give intermediate C. Intermediate C selectively undergoes the addition with • OH to afford intermediate D. Finally, oxidation ...