Tetrahedron

A convenient preparation of thioether functionalized porphyrins

MM Pollard, JC Vederas

Index: Pollard, Michael M.; Vederas, John C. Tetrahedron, 2006 , vol. 62, # 51 p. 11908 - 11915

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Abstract

This paper describes a convenient and high yielding three-step approach for the synthesis of trans-tetraphenylporphyrins possessing two thioethers in the ortho positions, which will facilitate the synthesis of more elaborate and complex porphyrin architectures. Their synthesis is realized by a double nucleophilic aromatic substitution of 2equiv of a thiolate on 2, 6-dichlorobenzaldehyde to generate a bis-thioether substituted benzaldehyde. This ...