New cytotoxic furoquinones obtained from terpenyl-1, 4-naphthoquinones and 1, 4-anthracenediones

…, SA Gualberto, C Cuevas, A San Feliciano

Index: Miguel del Corral, Jose M.; Castro, M. Angeles; Oliveira, Alaide B.; Gualberto, Simone A.; Cuevas, Carmen; Feliciano, Arturo San Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 21 p. 7231 - 7240

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Citation Number: 27

Abstract

A series of new furoterpenyl-1, 4-naphtho (anthra) quinones have been prepared via oxidative cyclization of the corresponding 2-hydroxy-3-butenyl-1, 4-naphtho (anthra) quinones. Depending on the reaction conditions the 1, 2-quinones or the 1, 4-quinones were obtained. Several new furo-1, 4-anthraquinones were also obtained by condensation of 2, 3-dichloroquinones with 1, 3-dicarbonyls. The compounds synthesized have been ...

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