Base-Mediated Aerobic Oxidation of Hagemann's Ester: Competitive Hydroxylation at C-1 and C-3 Positions

SH Kim, HS Lee, BR Park, JN Kim

Index: Kim, Sung Hwan; Lee, Hyun Seung; Park, Bo Ram; Kim, Jae Nyoung Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 5 p. 1725 - 1728

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Citation Number: 5

Abstract

The Hagemann's ester (Fig. 1) has been extensively used for the synthesis of various complex compounds. 1, 2 The reason might be due to its highly-functionalized nature and ready availability. 1, 2 The reaction of Hagemann's ester and an electrophile can occur theoretically at C-1, C-3, C-5, and C-2'positions (Fig. 1). As an example, however, it has been generally accepted that the site preference for alkylation was C-3, the resulting C-3- ...