Tetrahedron

Use of dichlorophthaloyl (DCPhth) group as an amino protecting group in oligosaccharide synthesis

M Lergenmüller, Y Ito, T Ogawa

Index: Lergenmueller, Matthias; Ito, Yukishige; Ogawa, Tomoya Tetrahedron, 1998 , vol. 54, # 8 p. 1381 - 1394

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Citation Number: 37

Abstract

As an alternative to phthaloyl (Phth) group, 4, 5-dichlorophthaloyl (DCPhth) group was investigated as an amino protecting group to prove it to be useful for the synthesis of β- glycosides of 2-acetamido-2-deoxy glucose (GlcNAc). DCPhth was introduced onto the C-2 nitrogen of glucosamine to give 2, which was further transformed into mono-and di-and trisaccharide derivatives which constitute basic structural units of asparagine linked ...