Helvetica Chimica Acta

Synthesis of a Trisaccharide Related to the Cytotoxic Triterpenoid Saponins Isolated from the Bark of Albizia procera

QC Liu, TT Guo, C Zhao, J Sun, WH Li

Index: Liu, Qing-Chao; Guo, Tian-Tian; Zhao, Cong; Sun, Jing; Li, Wen-Hong Helvetica Chimica Acta, 2014 , vol. 97, # 3 p. 361 - 368

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Abstract

Abstract Chemical synthesis of a trisaccharide related to the cytotoxic triterpenoid saponins isolated from the bark of Albizia procera has been accomplished through a concise stepwise glycosylation strategy starting from commercially available D-xylose, 2-acetamido-2-deoxy- D-glucose and L-arabinose. The target trisaccharide was designed with a 4-methoxyphenyl (MP) aglycone to extend the scope of conversion to suitable glycoconjugates via selective ...

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