Tetrahedron Letters

Chitosan-SO 3 H: an efficient, biodegradable, and recyclable solid acid for the synthesis of quinoline derivatives via Friedländer annulation

BVS Reddy, A Venkateswarlu, GN Reddy…

Index: Reddy, B.V. Subba; Venkateswarlu; Reddy, G. Niranjan; Reddy, Y.V. Rami Tetrahedron Letters, 2013 , vol. 54, # 43 p. 5767 - 5770

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Citation Number: 22

Abstract

Abstract Chitosan-SO 3 H is found to catalyze the Friedländer condensation/annulation reaction of 2-aminoaryl ketones with α-methyleneketones to produce the corresponding quinoline derivatives in high yields in short reaction times. The use of recyclable and biodegradable chitosan-SO 3 H makes this method quite simple, more convenient, and economically viable compared to acid catalyzed methods reported in the literature.

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