An efficient approach to quinolines via friedländer synthesis catalyzed by cuprous triflate

E Soleimani, MM Khodaei, N Batooie…

Index: Soleimani, Ebrahim; Khodaei, Mohammad Mehdi; Batooie, Nasim; Samadi, Saadi Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 2 p. 212 - 213

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Citation Number: 11

Abstract

As a privileged fragment, quinoline is a ubiquitous subunit in many quinoline-containing natural products with remark- able biological activities.1—6) Members of this family have wide applications in medicinal chemistry, being used as antimalarial, antiinflammatory agents, antiasthamatic, anti- bacterial, antihypertensive, and tyrosine kinase inhibiting agents.1—6) In addition, quinolines are valuable synthons used for the preparation of nano- and meso-structures with en- ...