A new, general, and convenient synthesis of 5-deazaflavins (5-deazaisoalloxazines)
T Nagamatsu, Y Hashiguchi, M Higuchi…
Index: Nagamatsu, Tomohisa; Hashigushi, Yuko; Higuchi, Masatsugu; Yoneda, Fumio Journal of the Chemical Society, Chemical Communications, 1982 , # 18 p. 1085 - 1086
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Citation Number: 11
Abstract
The condensation of 6-su bstituted-aminouracils with 0- ... 5-Deazaflavins (5-deazaisoalloxazines) have been studied extensively in both enzymatic1 and model systems2 to provide mechanistic insight into flavin-catalysed reactions. They have aroused further interest because of the recent discovery that coenzyme F420 from methanogenic bacteria possesses the 8- hydroxy-5-deazaflavin m~iety.~ Moreover, our findings that the oxidation of ...
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