A new synthetic method for the preparation of 5-deazaflavins and 5-deaza-10-oxaflavins
X Chen, M Nagata, K Tanaka, F Yoneda
Index: Chen, Xing; Nagata, Minako; Tanaka, Kiyoshi; Yoneda, Fumio Journal of the Chemical Society, Chemical Communications, 1989 , # 1 p. 44 - 45
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Abstract
The condensation of 6-chlorouracils with o-(substituted amino)benzyl alcohols and o-hydroxybenzyl alcohol gave directly 5-deazaflavin and 5-deaza-l O-oxaflavin derivatives, respectively. ... 5-Deazaflavins (5-deazaisoalloxazines) have received much attention since the discovery that some naturally occurring coenzymes possess the 8-hydroxy-5-deazaflavin moiety. 1 4 Existing methodologies for the synthesis of 5-deazaflavins involve (a) the condensation of ...
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