Investigation of the Cyclopentenone Formation via the α??Alkynone Cyclisation: Synthesis of the Acorone Intermediate 8??Methylspiro [4.5] deca??3, 7??dien??2??one
J Ackroyd, M Karpf, AS Dreiding
Index: Ackroyd, John; Karpf, Martin; Dreiding, Andre S. Helvetica Chimica Acta, 1985 , vol. 68, p. 338 - 344
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Citation Number: 16
Abstract
Abstract As a further application of the cyclopentenone formation A [RIGHTWARDS ARROW] Cvia the thermal α-alkynone cyclisation B [RIGHTWARDS ARROW] C and in order to test the fate of an isolated C, C-double bond within a molecule under these conditions, we investigated the synthesis of the acorone intermediate 3starting from the known carboxylic acid 1. The α-alkynone 2 was obtained from 1via the acyl chloride 6 and a Pd (II)- ...
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