Journal of the American Chemical Society

Acid amides as hypnotics. IV. Barbituric acids

FF Blicke, MF Zienty

Index: Blicke; Zienty Journal of the American Chemical Society, 1941 , vol. 63, p. 2991

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Citation Number: 7

Abstract

The known 5, 5-disubstituted barbituric acids in which one of the substituents is an arylalkyl, cycloalkylalkyl, alkoxyalkyl or aryloxyalkyl are relatively few in number. 5-Ethyl-5- benzylbarbituric acid, although a strong hypnotic, tends to produce convulsions. 3~ 4 The corresponding propyl and isopropyl compounds seem to be of little or no value. 4 5-Ethyl-5- @-phenylethylbarbituric acid lacks the convulsive property of the benzyl compound and is ...