Hypocholesterolemic agents. 7. C-17 epimer of 20, 25-diazacholesterol
RE Counsell, VV Ranade, F Kohen
Index: Ranade,V.V. et al. Journal of Medicinal Chemistry, 1971 , vol. 14, p. 38 - 40
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Citation Number: 9
Abstract
One approach to the development of hypocholesterolemic agents has been the synthesis of com-pounds which will inhibit the endogenous synthesis of cholesterol. Previous papers in the series described the synthesis and potent hypocholesteroleniic properties of certain aza- and diazncholest, erols. Sot only have these compounds been shown to inhibit cholesterol synthesis in laboratory animals3 arid man, 4 but, their ability to interfere with ...
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