A novel approach for the synthesis of aryl amides
A Shaabani, E Soleimani, AH Rezayan
Index: Shaabani, Ahmad; Soleimani, Ebrahim; Rezayan, Ali Hossein Tetrahedron Letters, 2007 , vol. 48, # 35 p. 6137 - 6141
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Citation Number: 58
Abstract
The classical method for the synthesis of amides is the reaction of carboxylic acids with amines at high temperature. Due to the low activity of carboxylic acids, various methods for their activation have been reported in the literature, 8 the most common being conversion of a carboxylic acid to a more reactive functional group, such as an acyl chloride, mixed anhydride, acyl azide, N-acylbenzotriazoles 9 or an active ester, or via in situ activation of the carboxylic group ...
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