Molecules

Substitutions of fluorine atoms and phenoxy groups in the synthesis of quinoxaline 1, 4-di-N-oxide derivatives

…, A Burguete, B Solano, S Ancizu, S Pérez-Silanes…

Index: Vicente, Esther; Villar, Raquel; Burguete, Asuncion; Solano, Beatriz; Ancizu, Saioa; Perez-Silanes, Silvia; Aldana, Ignacio; Monge, Antonio Molecules, 2008 , vol. 13, # 1 p. 86 - 95

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Citation Number: 6

Abstract

Abstract: The unexpected substitution of fluorine atoms and phenoxy groups attached to quinoxaline or benzofuroxan rings is described. The synthesis of 2-benzyl-and 2-phenoxy-3- methylquinoxaline 1, 4-di-N-oxide derivatives was based on the classical Beirut reaction. The tendency of fluorine atoms linked to quinoxaline or benzofuroxan rings to be replaced by a methoxy group when dissolved in an ammonia saturated solution of methanol was ...