Spontaneous resolution among chiral glycerol derivatives: crystallization features of ortho-alkoxysubstituted phenyl glycerol ethers

…, ZA Bredikhina, DV Zakharychev, LV Konoshenko

Index: Bredikhin, Alexander A.; Bredikhina, Zemfira A.; Zakharychev, Dmitry V.; Konoshenko, Larisa V. Tetrahedron Asymmetry, 2007 , vol. 18, # 16 p. 1964 - 1970

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Citation Number: 14

Abstract

Five chiral arylglycerol ethers 2-R-C6H4-O-CH2CH (OH) CH2OH (R= OMe, OEt, OPrn, OPri, OBut) have been prepared in racemic and enantiopure form. The melting points and enthalpies of fusion of every species were measured by differential scanning calorimetry. Binary phase diagrams were reconstructed for the whole family, the entropies of the mixing of the enantiomers in the liquid state, and Gibbs free energy of formation of the racemic ...

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