Synthesis of 2 H-1, 2-Benzothiazine 1, 1-Dioxides via Heteroannulation Reactions of 2-Iodobenzenesulfonamide with Ketone Enolates under SRN1 Conditions §

WJ Layman, TD Greenwood, AL Downey…

Index: Fontan, Rafael; Galvez, Carmen; Viladoms, Pere Heterocycles, 1981 , vol. 16, # 9 p. 1473 - 1474

Full Text: HTML

Citation Number: 28

Abstract

... Volume: Page: ... or 3,4-disubstituted-2H-1,2-benzothiazine 1,1-dioxides 2, whereas ester enolates would afford 2H-1,2-benzothiazin-3(4H)-one 1,1-dioxides 3. These heterocyclic annulation reactions ... 4, butanone, 15, 2c (R = H, R' = Et); 2d (R = R' = Me), 31; d 16, 9. ...

Related Articles:

A novel series of parenteral cephalosporins exhibiting potent activities against Pseudomonas aeruginosa and other Gram-negative pathogens: Synthesis and …

[Yamawaki, Kenji; Nomura, Takashi; Yasukata, Tatsuro; Uotani, Koichi; Miwa, Hideaki; Takeda, Kei; Nishitani, Yasuhiro Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 21 p. 6716 - 6732]

Synthesis of pyrrolopyridines (azaindoles)

[Mahadevan,Indumathy; Rasmussen, Malcolm Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 2 p. 359 - 367]

Palladium-catalyzed reductive N-heterocyclization of alkenyl-substituted nitroarenes as a viable method for the preparation of bicyclic pyrrolo-fused heteroaromatic …

[Gorugantula, Sobha P.; Carrero-Martinez, Grissell M.; Dantale, Shubhada W.; Soederberg, Bjoern C.G. Tetrahedron, 2010 , vol. 66, # 10 p. 1800 - 1805]

Novel 3-azaindolyl-4-arylmaleimides exhibiting potent antiangiogenic efficacy, protein kinase inhibition, and antiproliferative activity

[Cash, Michael T.; Schreiner, Peter R.; Phillips, Robert S. Organic and Biomolecular Chemistry, 2005 , vol. 3, # 20 p. 3701 - 3706]

Novel 3-azaindolyl-4-arylmaleimides exhibiting potent antiangiogenic efficacy, protein kinase inhibition, and antiproliferative activity

[Cash, Michael T.; Schreiner, Peter R.; Phillips, Robert S. Organic and Biomolecular Chemistry, 2005 , vol. 3, # 20 p. 3701 - 3706]

More Articles...