A mild and chemoselective method for ester O-alkyl cleavage using in situ generated potassium thiophenoxide from catalytic quantities of base

L Sharma, MK Nayak, AK Chakraborti

Index: Sharma, Lalima; Nayak, Mrinal K.; Chakraborti, Asit K. Tetrahedron, 1999 , vol. 55, # 31 p. 9595 - 9600

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Citation Number: 21

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Chemoselective deprotection of methyl esters can be achieved under non-hydrolytic and virtually neutral conditions by treatment with thiophenol in N-methyl-2-pyrrolidone (NMP) in the presence of a catalytic amount of K 2 CO 3 . ... Various substituted aryl and alkyl carboxylic acids, ...