MgCl2??Accelerated Addition of Functionalized Organozinc Reagents to Aldehydes, Ketones, and Carbon Dioxide

A Metzger, S Bernhardt, G Manolikakes…

Index: Metzger, Albrecht; Bernhardt, Sebastian; Manolikakes, Georg; Knochel, Paul Angewandte Chemie - International Edition, 2010 , vol. 49, # 27 p. 4665 - 4668

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Citation Number: 100

Abstract

Organozinc compounds are important organometallic reagents for organic synthesis, since they tolerate a broad range of functional groups.[1] Their intrinsic moderate reactivity towards electrophiles can be dramatically increased by transmetalation with catalytic amounts of various transitionmetal complexes of Pd,[2] Ni,[3] Cu,[4] Fe,[5] Co,[6] and other metal salts.[7] However, such transmetalations are less appropriate for reactions with ...