A Convenient Methodology for the Selective Reduction of Carboxylic Acids With Benzyltriethyl-Ammonium Borohydride—Chlorotrimethylsilane
J Das, S Chandrasekaran
Index: Das, J.; Chandrasekaran, S. Synthetic Communications, 1990 , vol. 20, # 6 p. 907 - 912
Full Text: HTML
Citation Number: 17
Abstract
A combination of benzyltriethylammonium borohydride and chlorotrimethylsilane (1:l) in dichloromethane (0-25OC) has been found to be a convenient reagent system for the selective reduction ofcarboxylicacidstoal cohols . ... Recently we reported our results on the facile and ... The mechanism of this reaction and active species ... Unlike borane this reagent system reduces benzoyl ... H3C(CH,),6 COOH 4 H3C (CH2) 16CH20H 97 ... H3C(CH2)3COOH 4 H3C(CH2)3 CH20H 85
Related Articles:
[Saxena, Ira; Deka, Nabajyoti; Sarma, Jadab C.; Tsuboi, Sadao Synthetic Communications, 2003 , vol. 33, # 23 p. 4005 - 4011]
[Uchiyama, Masanobu; Furumoto, Shozo; Saito, Mariko; Kondo, Yoshinori; Sakamoto, Takao Journal of the American Chemical Society, 1997 , vol. 119, # 47 p. 11425 - 11433]
[Saxena, Ira; Deka, Nabajyoti; Sarma, Jadab C.; Tsuboi, Sadao Synthetic Communications, 2003 , vol. 33, # 23 p. 4005 - 4011]
Catalytic hydrogenation of unactivated amides enabled by hydrogenation of catalyst precursor
[Tetrahedron Letters, , vol. 54, # 21 p. 2674 - 2678]
[Brown, Herbert C.; Narasimhan, S.; Choi, Yong Moon Journal of Organic Chemistry, 1982 , vol. 47, # 24 p. 4702 - 4708]