Design, reactivities, and practical application of dialkylzinc hydride ate complexes generated in situ from dialkylzinc and metal hydride. A new methodology for …

M Uchiyama, S Furumoto, M Saito…

Index: Uchiyama, Masanobu; Furumoto, Shozo; Saito, Mariko; Kondo, Yoshinori; Sakamoto, Takao Journal of the American Chemical Society, 1997 , vol. 119, # 47 p. 11425 - 11433

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Citation Number: 79

Abstract

We designed various dialkylzinc hydride “ate” complexes, prepared from dialkylzinc and metal hydride, and investigated the reactivities (and the transference aptitude of ligands) of these zincates toward benzophenone. The results clearly reveal that dimethylzinc hydrides are the most powerful and selective zincates for the reduction of the carbonyl group. This complex reagent turned out to be effective for the reduction of esters and amides as well ...

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