Reactions of anthranilamide with isocyanates: A new facile synthesis of 2, 3??dihydro??5H??oxazolo [2, 3??b] quinazolin??5??one and 3, 4??dihydro??2H, 6H??[1, 3] oxazino [2, …

JW Chern, FJ Shish, CD Chang…

Index: Chern, Ji-Wang; Shish, Fang-Jy; Chang, Chau-Dung; Chan, Chao-Han; Liu, Kang-Chien Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 1103 - 1105

Full Text: HTML

Citation Number: 7

Abstract

Abstract 2, 3-Dihydro-5H-oxazolo [2, 3-b] quinazolin-5-one 5a was synthesized from anthranilamide 1 and 2-chloro-ethyl isocyanate either by a direct reflux in methanol, or by stirring at room temperature in acetonitrile leading to the intermediate, 2-(2-chloroethyl ureido) benzamide 6a which was subsequently cyclized on heating with an organic base. However, when compound 6a was refluxed with concentrated hydrochloric acid, it ...

Related Articles:

Reactions of o??aminonitriles with isocyanates. 1. A two??step synthesis of 2, 6??dihydroimidazo [1, 2??c] quinazolin??5??(3H) one

[Papadopoulos, Eleftherios Paul Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1553 - 1558]

Reactions of o??aminonitriles with isocyanates. 1. A two??step synthesis of 2, 6??dihydroimidazo [1, 2??c] quinazolin??5??(3H) one

[Papadopoulos, Eleftherios Paul Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1553 - 1558]

Reactions of o??aminonitriles with isocyanates. 1. A two??step synthesis of 2, 6??dihydroimidazo [1, 2??c] quinazolin??5??(3H) one

[Papadopoulos, Eleftherios Paul Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1553 - 1558]

… the Synthesis of Ketanserin () and its Hydrochloride Salt () via 3??(2??Chloroethyl)??2, 4??(1H, 3H)??quinazolinedione () or Dihydro??5H??oxazole (2, 3??b) quinazolin??5??one …

[Fakhraian, Hossein; Heydary, Mehdi Journal of Heterocyclic Chemistry, 2014 , vol. 51, # 1 p. 151 - 156]

… the Synthesis of Ketanserin () and its Hydrochloride Salt () via 3??(2??Chloroethyl)??2, 4??(1H, 3H)??quinazolinedione () or Dihydro??5H??oxazole (2, 3??b) quinazolin??5??one …

[Fakhraian, Hossein; Heydary, Mehdi Journal of Heterocyclic Chemistry, 2014 , vol. 51, # 1 p. 151 - 156]

More Articles...