Enzymic Synthesis and Regeneration of 3'-Phosphoadenosine 5'-Phosphosulfate (PAPS) for Regioselective Sulfation of Oligosaccharides

…, GJ Shen, E Garcia-Junceda, CH Wong

Index: Lin; Shen; Garcia-Junceda; Wong Journal of the American Chemical Society, 1995 , vol. 117, # 30 p. 8031 - 8032

Full Text: HTML

Citation Number: 45

Abstract

Sulfated biomolecules play important roles in many biological processes.'The sulfated Lea tetra-and pentasaccharides, Ib for example, are potent inhibitors of the cell adhesion molecule P-seiectin, and sialyl Lewis x with a sulfate group at the 6-position of galactose is a ligand for L-selectin. Ic Many glycosaminoglycans such as heparin and dermatan sulfate are also sulfated and are involved in numerous cellular functions.'df In addition, the sulfation ...

Related Articles:

Isolation and identification of diadenosine 5′, 5‴-P 1, P 4-tetraphosphate binding proteins using magnetic bio-panning

[Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 23 p. 7175 - 7179]

Convenient Synthesis of Nucleoside??5′??Diphosphates from the Corresponding Ribonucleoside??5′??phosphoroimidazole

[Kore, Anilkumar R.; Parmar, Gaurang Synthetic Communications, 2006 , vol. 36, # 22 p. 3393 - 3399]

Practical enzymic synthesis of adenosine 5'-0-(3-thiotriphosphate)(ATP-. gamma.-S)

[Abril, Obsidiana; Crans, Debbie C.; Whitesides, George M. Journal of Organic Chemistry, 1984 , vol. 49, p. 1360 - 1364]

Enzymatic synthesis of UTPγS, a potent hydrolysis resistant agonist of P2U??purinoceptors

[British Journal of Pharmacology, , vol. 117, # 1 p. 203 - 209]

Wide sugar substrate specificity of galactokinase from Streptococcus pneumoniae TIGR4

[Carbohydrate Research, , vol. 346, # 15 p. 2421 - 2425]

More Articles...