Total synthesis of L-biopterin from L-tartaric acid via 5-deoxy-L-arabinose
AM Fernandez, L Duhamel
Index: Fernandez, Anne-Marie; Duhamel, Lucette Journal of Organic Chemistry, 1996 , vol. 61, # 24 p. 8698 - 8700
Full Text: HTML
Citation Number: 18
Abstract
L-Biopterin (1), one of the most ubiquitous compounds in the class of the naturally occurring pterins, was isolated from human urine as a growth factor of Crithidia fasciculata by Patterson et al. 1 Through its 5, 6, 7, 8-tetrahydro form, 1 functions as an essential enzyme cofactor in the conversion of phenylalanine to tyrosine2 and tyrosine to DOPA, 3 in melanine synthesis, 4 and in tryptophan hydroxylation. 5 As a consequence, tetrahydrobiopterin has ...
Related Articles:
[Murata; Sugimoto; Ogiwara; Mogi; Wasada Synthesis, 1992 , # 3 p. 303 - 308]
Photochemistry of dihydrobiopterin in aqueous solution
[Organic and Biomolecular Chemistry, , vol. 8, # 4 p. 800 - 810]
[Synthesis, , # 3 p. 303 - 308]
[Synthesis, , # 3 p. 303 - 308]
[Synthesis, , # 3 p. 303 - 308]