Synthetic studies on statins. Part 1: a short and cyanide-free synthesis of atorvastatin calcium via an enantioselective aldol strategy
L Hu, F Xiong, X Chen, W Chen, Q He, F Chen
Index: Tetrahedron Asymmetry, , vol. 24, # 4 p. 207 - 211
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Citation Number: 10
Abstract
... Tetrahedron: Asymmetry. Volume 24, Issue 4, 28 February 2013, Pages 207–211. ... 9 The Michael addition of acrolein and sodium nitrite in HOAc/THF/H 2 O at 0 °C proceeded smoothly to afford nitroaldehyde 4 in 89% yield, which was protected as a diethyl acetal upon treatment ...
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