Tetrahedron letters

Heck reaction of aryl halides with linear or cyclic alkenes catalysed by a tetraphosphine/palladium catalyst

F Berthiol, H Doucet, M Santelli

Index: Berthiol, Florian; Doucet, Henri; Santelli, Maurice Tetrahedron Letters, 2003 , vol. 44, # 6 p. 1221 - 1225

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Citation Number: 52

Abstract

cis, cis, cis-1, 2, 3, 4-Tetrakis (diphenylphosphinomethyl) cyclopentane/[PdCl (C3H5)] 2 system catalyses efficiently the Heck reaction of aryl halides with linear alkenes such as pent- 1-ene, oct-1-ene or dec-1-ene. Selectivities up to 70% in favour of E-1-arylalk-1-ene isomers can be obtained. In the presence of cyclic alkenes the selectivities of the reactions strongly depends on the ring size. Addition to cyclohexene or cycloheptene led mainly to 1- ...

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