A new protocol for a one-pot synthesis of α-amino phosphonates by reaction of imines prepared in situ with trialkylphosphites
MR Saidi, N Azizi
Index: Saidi, Mohammad R.; Azizi, Najmedin Synlett, 2002 , # 8 p. 1347 - 1349
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Citation Number: 82
Abstract
During the course of our efforts towards the aminoalkylation of aldehydes mediated by lithium perchlorate in diethyl ether, [9] we found that an imines prepared in situ react very effectively with trimethylphosphite or triethylphosphite as nucleophile to produce α-amino phosphonates. In the present work, we attempted to develop a novel one-pot and fast procedure for the preparation of α-amino phosphonates at ambient temperature. It was found that the ...
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