Synthesis of Pyrrolidine Derivatives by the Palladium??Catalyzed Cyclization of N??(2??Cyclohexenyl) bromoacetamide Derivatives
SC Yang, FH Tseng, CW Hung
Index: Yang, Shyh-Chyun; Tseng, Fu-Hsiung; Hung, Chung-Wei Journal of the Chinese Chemical Society, 1999 , vol. 46, # 2 p. 211 - 214
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Abstract
Shyh-Chyun Yang* ( t~i!tfF ),Fu-Hsiung Tseng ( 1W~m )and Chung-Wei Hung ( '1iffal- ) Graduate Institute ofPharmaceutical Sciences, Kaohsiung Medical Coilege, Kaohsiung 80708, Taiwan, R.OC ... N-(2·Cyclohexenyl)bromoacetarnide derivatives underwent intramolecular cyclization to give pyrrolid- inc derivatives in the presence of a base and a catalytic amount of palladium catalyst. ... ~ ~2 4:1, R,=H BrC-(,lIlJ, h. R;~Me ... I R, In.RI~Bn h, R1=f'h
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