Palladium-catalyzed hydroamination of 1, 3-dienes: a colorimetric assay and enantioselective additions

O Löber, M Kawatsura, JF Hartwig

Index: Loeber; Kawatsura; Hartwig Journal of the American Chemical Society, 2001 , vol. 123, # 18 p. 4366 - 4367

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Citation Number: 208

Abstract

Mild, selective 1: 1 reactions of amines with dienes to form allylic amines are rare1 and limited to the reaction of cyclic dialkylamines catalyzed by nickel. 2 Late transition metalcatalyzed, amine-induced telomerizations of butadiene1 and oxidative 1, 4 addition of nucleophiles to dienes3 are now well known, and the palladium-catalyzed additions of amines to more reactive eneynes4 and allenes5 have been reported. However, reactions ...

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