A direct method for the synthesis of indolizine derivatives from easily available aromatic ketones, pyridines, and acrylonitrile derivatives

Q Cai, YP Zhu, Y Gao, JJ Sun…

Index: Cai, Qun; Zhu, Yan-Ping; Gao, Yang; Sun, Jing-Jing; Wu, An-Xin Canadian Journal of Chemistry, 2013 , vol. 91, # 6 p. 414 - 419

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Abstract

A concise and efficient strategy has been proposed to synthesize indolizine derivatives from easily available aryl or heteroaryl methyl ketones, pyridines, and acrylonitriles. The mechanistic pathway involved the integration of iodination, pyridinium ylide synthesis, and 1,

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