Synthesis of ortho-phenyl substituted MeO-BIPHEP ligand and its application in Rh-catalyzed asymmetric hydrogenation
S Wu, M He, X Zhang
Index: Wu, Shulin; He, Minsheng; Zhang, Xumu Tetrahedron Asymmetry, 2004 , vol. 15, # 14 p. 2177 - 2180
Full Text: HTML
Citation Number: 33
Abstract
A new BIPHEP-type ligand with phenyl groups at the 3, 3′-positions, o-Ph-MeO-BIPHEP 3 was prepared. This ligand afforded excellent enantioselectivities when used in the Rh- catalyzed asymmetric hydrogenation of α-dehydroamino acid derivatives. The strong influence of o-phenyl groups of the ligand on the enantioselectivities of the reaction has been demonstrated by a comparison with its parent ligand MeO-BIPHEP.
Related Articles:
Synthesis, resolution and applications of 3, 3′-bis (RO)-MeO-BIPHEP derivatives
[Gorobets, Evgueni; Sun, Guang-Ri; Wheatley, Bronwen M.M.; Parvez, Masood; Keay, Brian A. Tetrahedron Letters, 2004 , vol. 45, # 18 p. 3597 - 3601]
[Brown, John M.; Woodward, Simon Journal of Organic Chemistry, 1991 , vol. 56, # 24 p. 6803 - 6809]
Synthesis, resolution and applications of 3, 3′-bis (RO)-MeO-BIPHEP derivatives
[Gorobets, Evgueni; Sun, Guang-Ri; Wheatley, Bronwen M.M.; Parvez, Masood; Keay, Brian A. Tetrahedron Letters, 2004 , vol. 45, # 18 p. 3597 - 3601]
Synthesis, resolution and applications of 3, 3′-bis (RO)-MeO-BIPHEP derivatives
[Gorobets, Evgueni; Sun, Guang-Ri; Wheatley, Bronwen M.M.; Parvez, Masood; Keay, Brian A. Tetrahedron Letters, 2004 , vol. 45, # 18 p. 3597 - 3601]
Synthesis, resolution and applications of 3, 3′-bis (RO)-MeO-BIPHEP derivatives
[Gorobets, Evgueni; Sun, Guang-Ri; Wheatley, Bronwen M.M.; Parvez, Masood; Keay, Brian A. Tetrahedron Letters, 2004 , vol. 45, # 18 p. 3597 - 3601]