Sulfenylation of some pyrroles and indoles

HM Gilow, CS Brown, JN Copeland…

Index: Gilow, Helmuth M.; Brown, Christopher S.; Copeland, John N.; Kelly, Keith E. Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 4 p. 1025 - 1034

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Citation Number: 30

Abstract

Abstract Methylsulfenylation of 1-substituted pyrroles and indoles was observed using 1- (methylthio) morpholine and an acid catalyst or with methylsulfenyl chloride and excess pyridine. 1-Substituents which are activating or weakly deactivating towards electrophilic substitution such as alkyl, 2-cyanoethyl, dimethylamino, trialkylsilyl, 2-chloroethyl and 2- phenylsulfonylethyl were used. The 2-chloroethyl and 2-phenylsulfonylethyl groups which ...