The first example of a diastereoselective thio-Ugi reaction: A new synthetic approach to chiral imidazole derivatives
AV Gulevich, ES Balenkova…
Index: Merrett, John H.; Spurden, William C.; Thomas, W Anthony; Tong, Brian P.; Whitcombe, Ian W. A. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 61 - 68
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Citation Number: 50
Abstract
... B). Amidine 3 (R 1 = Bn, R 2 = 4-ClPh) was isolated in a yield of 82% and was characterized by 1 H NMR and 13 C NMR spectra. ... unprotected 2-aminoalkylimidazoles 4 in good yield (Table 3). A few thioamides, such as the α,α-disubstituted thioamides 2n−p, prepared from ...
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