The Journal of Organic Chemistry

Functionalized deep-cavity cavitands

H Xi, CLD Gibb, BC Gibb

Index: Xi, Huaping; Gibb, Corinne L. D.; Gibb, Bruce C. Journal of Organic Chemistry, 1999 , vol. 64, # 25 p. 9286 - 9288

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Citation Number: 45

Abstract

In the development of efficient artificial enzymes1-6 possessing preorganized catalytic machinery, a primary consideration for chemists is the choice of scaffold used to arrange and hold the requisite functional groups in the necessary three-dimensional array. This scaffold, acting as a surrogate for the bulk of the main chain of the target enzyme, must therefore possess three important aspects. First, the chemical architecture of the scaffold ...