Development of a scalable synthetic process for selective bromination of 4-methyl-3, 7-substituted coumarins

…, RK Russell, R Ma, S Branum, J Xu…

Index: Waykole, Liladhar; Prashad, Mahavir; Palermo, Stephen; Repic, Oljan; Blacklock, Thomas J. Synthetic Communications, 1997 , vol. 27, # 12 p. 2159 - 2163

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Abstract

... Volume: Page: ... Development of a Scalable Synthetic Process for Selective Bromination of 4-Methyl-3,7-Substituted Coumarins. ... by HPLC) along with 40% of 4-dibromomethyl 8a and 25% of aromatic bromination product 10a (Scheme 2). 12 The addition of ...

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