[Pd (PPh 3) 2 (saccharinate) 2]—general catalyst for Suzuki–Miyaura, Negishi cross-coupling and C–H bond functionalization of coumaryl and pyrone substrates

P Shah, MD Santana, J García, JL Serrano, M Naik…

Index: Shah, Parin; Santana, M. Dolores; Garcia, Joaquin; Serrano, J. Luis; Naik, Minal; Pednekar, Suhas; Kapdi, Anant R. Tetrahedron, 2013 , vol. 69, # 5 p. 1446 - 1453

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Citation Number: 27

Abstract

The potential of complex [Pd (PPh3) 2 (saccharinate) 2] 1 in catalyzing Suzuki–Miyaura cross-coupling of 4-halo and 4-bromomethyl coumaryl and pyrone substrates with different aryl boronic acids has been explored. Excellent yields of the desired products are obtained in competitive reaction time and under relatively mild conditions. Negishi cross-coupling of 4- coumaryl tosylate with aryl and alkylzinc reagents has also been performed with good ...