Tetrahedron

Palladium-catalyzed domino protodecarboxylation/oxidative Heck reaction: regioselective arylation of coumarin-3-carboxylic acids

…, F Molaverdi, M Alipour, F Jafarpour, A Foroumadi…

Index: Khoobi, Mehdi; Molaverdi, Fatemeh; Alipour, Masoumeh; Jafarpour, Farnaz; Foroumadi, Alireza; Shafiee, Abbas Tetrahedron, 2013 , vol. 69, # 52 p. 11164 - 11168

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Citation Number: 6

Abstract

Abstract A protocol for straightforward and step-economical synthesis of neoflavones from coumarin-3-carboxylic acids is developed. This approach enables controlled protodecarboxylation/regioselective C–H arylation of coumain-3-carboxylic acids in one-pot using a monometallic catalytic system. A wide variety of electron-donating and-withdrawing substituents on both coumarins and arylboronic acid are tolerated under the reaction ...

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