Palladium??Based Nanocatalyst for One??Pot Synthesis of Polysubstituted Quinolines

BWJ Chen, LL Chng, J Yang, Y Wei, J Yang…

Index: Chen, Benjamin Wei Jie; Chng, Leng Leng; Yang, Jun; Wei, Yifeng; Yang, Jinhua; Ying, Jackie Y. ChemCatChem, 2013 , vol. 5, # 1 p. 277 - 283

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Citation Number: 9

Abstract

Abstract The synthesis of quinolines has been achieved through a one-pot, two-step tandem reaction catalyzed with Ag [BOND] Pd alloy nanoparticles supported on carbon. Ag [BOND] Pd alloy nanoparticles catalyzed the coupling of a ketone with a primary alcohol through a hydrogen autotransfer process, which yields α-alkylated ketones under an Ar flow. These are reacted with 2-aminobenzyl alcohols in a modified Friedländer synthesis to give ...

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