Synthesis and antimicrobial activity of substituted 4-aryl-3-phenylhydrazono-2, 4-dioxobutanoic acids
EV Pimenova, RA Khamatgaleev, EV Voronina…
Index: Pimenova; Khamatgaleev; Voronina; Andreichikov Pharmaceutical Chemistry Journal, 1999 , vol. 33, # 8 p. 424 - 426
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Abstract
In continuation of the previous investigations into the pharmacological activity of aroylpyruvic acid amides [1], we have synthesized a series of new compounds &this class, con- taining [3-arylhydrazone fragments, and assessed their activity in comparison with that of the other reported amides [2]. Interactions of 1-phenyl-3-aroyl-4,5-dihydro-4,5-pyra- zolodiones (I) with primary aromatic amines and secondary cyclic amines (morpholine and piperidine) led to the ...
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