Synthesis, characterization and derivatization of some novel types of mono-and bis-imidazolidineiminothiones and imidazolidineiminodithiones with antitumor, …
AMS El-Sharief, Z Moussa
Index: El-Sharief, Ahmed M. Sh.; Moussa, Ziad European Journal of Medicinal Chemistry, 2009 , vol. 44, # 11 p. 4315 - 4334
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Citation Number: 15
Abstract
Halogenated and alkylated N-arylcyanothioformanilides were reacted with the nucleophilic reagents triethylamine, hydrazine and diphenyldiazomethane to produce N- arylcyanothioformanilide ammonium salts, a thiosemicarbazide and a 2-(arylamino)-3, 3- diphenylacrylonitrile, respectively. They also underwent several types of electrophilic reactions with aryl-, arylbisisocyanates and arylisothiocyanates to yield mono-and bis- ...
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