High threo diastereoselectivity via europium (III)-catalyzed cyclocondensation of a silyloxy diene with. alpha.-alkoxy aldehydes. Synthesis of (-) pestalotin
MM Midland, RS Graham
Index: Midland, M. Mark; Graham, Richard S. Journal of the American Chemical Society, 1984 , vol. 106, # 15 p. 4294 - 4296
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Citation Number: 74
Abstract
Lewis acid catalyzed cyclocondensation of silyloxy dienes with dieneophiles has become a powerful method of constructing complex structures in a single step.'The cyclocondensation of the appropriately substituted diene with an aldehyde or ketone provides a potentially efficient and convergent method of synthesizing a variety of Since our research group is interested in the asymmetric synthesis of y-and M a~ tones,~ we chose to investigate the ...
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