Manganese-catalyzed aerobic dehydrogenative cyclization toward ring-fused indole skeletons

K Oisaki, J Abe, M Kanai

Index: Oisaki, Kounosuke; Abe, Junpei; Kanai, Motomu Organic and Biomolecular Chemistry, 2013 , vol. 11, # 28 p. 4569 - 4572

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Citation Number: 15

Abstract

We describe the first example of manganese (III)-catalyzed aerobic dehydrogenative cyclization producing ring-fused indole skeletons. This catalytic system converts from two C– H bonds of indole and malonate to a C–C bond and produces water as the sole side product. This operationally easy method was extended to an intermolecular cross- dehydrogenative coupling of indole and α-substituted malonate with complete C2- ...