Studies on the preparation of 2-(trifluoromethyl) acrylic acid and its esters from 3, 3, 3-trifluoropropene via hydrocarbonylation reactions
C Botteghi, C Lando, U Matteoli, S Paganelli…
Index: Botteghi, Carlo; Lando, Claudia; Matteoli, Ugo; Paganelli, Stefano; Menchi, Gloria Journal of Fluorine Chemistry, 1997 , vol. 83, # 1 p. 67 - 71
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Citation Number: 11
Abstract
The synthesis of methyl α-(trifluoromethyl) acrylate (MTFMA) has been carried out in three steps starting from commercially available 3, 3, 3.-trifluoropropene; this route involving the cobalt-catalyzed carbonylation of 2-bromo-3, 3, 3-trifluoropropene (2-Br-TFP) under very mild reaction conditions, gave only about 30% yield of the desired methyl ester. 2- (Trifluoromethyl) propanal, available in 90% yield by rhodium catalyzed hydroformylation ...
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