Angewandte Chemie International Edition

S??Nitrosothiol Chemistry at the Single??Molecule Level

LS Choi, H Bayley

Index: Choi, Lai-Sheung; Bayley, Hagan Angewandte Chemie - International Edition, 2012 , vol. 51, # 32 p. 7972 - 7976

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Citation Number: 6

Abstract

Nitric oxide (NO) and its relatives (notably RSNO and HNO) perform important roles as regulatory molecules in health and disease.[1] NO activates guanylate cyclase by binding to its ferrous heme (see the Supporting Information, Figure S1). The lifetime of NO is short, being milliseconds to seconds,[1b] and therefore it is unlikely that NO diffuses more than approximately 100 μm, which is in the range of a few cells, from the site at which it is ...