Tetrahedron

Study towards bioactive pyrone derivatives from the marine red alga Phacelocarpus labillardieri

D Song, G Blond, A Fürstner

Index: Song, Dschun; Blond, Gaelle; Fuerstner, Alois Tetrahedron, 2003 , vol. 59, # 35 p. 6899 - 6904

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Citation Number: 26

Abstract

Red algae of the genus Phacelocarpus labillardieri produce a structurally rather unique class of macrocyclic pyrone derivatives with phospholipase A2 inhibiting properties and potential neuromuscular blocking activity. They were also shown to be potent feeding inhibitors for various marine herbivorous gastropods. Described herein is the first preparative study towards these conspicuous secondary metabolites. Their carbon ...