Synthesis of some pyrazole derivatives and preliminary investigation of their affinity binding to P-glycoprotein

F Manna, F Chimenti, R Fioravanti, A Bolasco…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 20 p. 4632 - 4635

Full Text: HTML

Citation Number: 135

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... designing new, potent selective, and less toxic anticancer agents is still a major challenge to medicinal chemistry researchers. ... The chemical and physical data are reported in Table 1. The microanalyses of derivatives 2a–u are reported ...