A simple, rapid, and efficient N-Boc protection of amines under ultrasound irradiation and catalyst-free conditions
A Amira, H K'tir, M Berredjem, NE Aouf
Index: Amira, Aicha; K'Tir, Hacene; Berredjem, Malika; Aouf, Nour-Eddine Monatshefte fur Chemie, 2014 , vol. 145, # 3 p. 509 - 515
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Citation Number: 14
Abstract
Abstract A green and simple approach for the N-Boc protection on structurally diverse amines under ultrasound irradiation is described. Selective N-Boc protection was achieved in excellent isolated yield in a short reaction time at room temperature. Mild conditions, inexpensive and an easily available reagent, and absence of any auxiliary substances are the main advantages of this procedure. Graphical abstract
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