CuI-Catalyzed Coupling of gem-Dibromovinylanilides and Sulfonamides: An Efficient Method for the Synthesis of 2-Amidoindoles and Indolo [1, 2-a] quinazolines
SE Kiruthika, PT Perumal
Index: Kiruthika, Selvarangam E.; Perumal, Paramasivan Thirumalai Organic Letters, 2014 , vol. 16, # 2 p. 484 - 487
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Citation Number: 17
Abstract
A Cu (I)-catalyzed, intermolecular protocol for the synthesis of 2-amidoindoles and tetrahydroindolo [1, 2-a] quinazolines in shorter time and high yields is reported. The key highlight of this disclosure is the formation of 2-amidoindole and tetrahydroindolo [1, 2-a] quinazoline moieties directly from gem-dibromovinylanilides and sulfonamides in a one-pot fashion through the in situ formation of ynamides followed by a base-promoted ...
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