Novel Asymmetric Synthesis of (S)-Esmolol Using Hydrolytic Kinetic Resolution
AV Narsaiah, JK Kumar
Index: Narsaiah, A. Venkat; Kumar, J. Kranthi Synthetic Communications, 2011 , vol. 41, # 11 p. 1603 - 1608
Full Text: HTML
Citation Number: 8
Abstract
Abstract An efficient asymmetric synthesis of (S)-methyl 3-[4-[2-hydroxy-3-(isopropyl amino) propoxy] phenyl] propanoate is described. The key intermediate (S)-methyl 3-[4-(oxiran-2- ylmethoxy) phenyl] propanoate was obtained by hydrolytic kinetic resolution method using Jacobsen catalyst.
Related Articles:
The New Metabolite (S)??Cinnamoylphosphoramide from Streptomyces sp. and Its Total Synthesis
[Quitschau, Melanie; Schuhmann, Tim; Piel, Joern; Von Zezschwitz, Paultheo; Grond, Stephanie European Journal of Organic Chemistry, 2008 , # 30 p. 5117 - 5124]
[Pearson, Andrew G.; Kiefel, Milton J.; Ferro, Vito; Von Itzstein, Mark Carbohydrate Research, 2005 , vol. 340, # 13 p. 2077 - 2085]
A simple and effective method for chemoselective esterification of phenolic acids
[Guo, Wei; Li, Junfei; Fan, Ningjuan; Wu, Weiwei; Zhou, Peiwen; Xia, Chizhong Synthetic Communications, 2005 , vol. 35, # 1 p. 145 - 152]
[Lee, Seung Young; Moon, Eunjung; Kim, Sun Yeou; Lee, Kang Ro Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 7 p. 2140 - 2144]
[Lee, Seung Young; Moon, Eunjung; Kim, Sun Yeou; Lee, Kang Ro Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 7 p. 2140 - 2144]