5-Bromo-6-methoxy-8-aminoquinoline and its Transformation to 7-Bromo-6-methoxy-8-aminoquinoline1

WM Lauer, CJ Claus, RWV Korff…

Index: Lauer et al. Journal of the American Chemical Society, 1952 , vol. 74, p. 2080

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Citation Number: 4

Abstract

The preparation of 5-bromo-6-methoxy-8-aminoquinoline is described. It was found that this substance is transformed into its isomer, 6-methoxy-7-bromo-8-aminoquinoline, by means of boiling hydrobromic acid. This transformation gives evidence for the positive character of the bromine atom in the 5-position of 5-bromo-6-methoxy-8-aminoquinoline.